Nail Lacquer for Onychomycosis | 24 Jun 2019

Researchers from the Delhi-based Hamdard Institute of Medical Sciences and Research have developed a novel translucent nail lacquer fortified with an antifungal drug Luliconazole to treat onychomycosis.

• This drug-infused, quick-drying polymer can be easily applied like nail polish.
• The researchers tested the polymer on bovine hooves, as their outer structure is similar to that of the human nails. Over the 24 hours, 75% of the drug was released to the nail exhibiting its ability for prolonged drug delivery.

Onychomycosis

• It is a fungal infection of the nails that causes discoloration, thickening, and separation from the nail bed.
• It is caused by a variety of organisms, but most cases are caused by dermatophytes (fungi).
• It affects toenails more often than fingernails because of their slower growth, reduced blood supply, and frequent confinement in dark, moist environments.
• Accurate diagnosis involves physical and microscopic examination and culture.
• The treatment is aimed at eradication of the causative organism and return to a normal appearance of the nail.