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Guillain-Barré Syndrome and BBE

  • 03 Feb 2025
  • 2 min read

Source: IE 

Pune reported a case of Bickerstaff’s Brainstem Encephalitis (BBE), a rare variant of Guillain-Barré syndrome (GBS). 

  • GBS: It is a rare neurological disorder where the body's immune system attacks the peripheral nervous system (PNS) (controls muscle movement and sensory functions). 
    • Symptoms: Range from mild weakness to severe paralysis, including breathing difficulties. 
    • Treatment: No known cure for GBS. Intravenous immunoglobulin (IVIG), derived from healthy blood donations, can aid in recovery. 
  • BBE: It is a rare, rapidly progressive, post-infectious neurological disorder where the brainstem becomes inflamed. 
    • Symptoms: Mild respiratory infections or diarrheal illness, ataxia (loss of muscle control), ophthalmoplegia (paralysis of eye muscles), and weakness of limbs. 
    • Treatment: IVIG is commonly used to treat the condition. 
  • BBE and GBS: BBE affects the central nervous system (CNS), while GBS impacts the PNS. 
    • BBE is caused by an autoimmune response (the body's immune system attacks its own tissues) after an infection, while GBS is triggered by infection, vaccination, or surgery. 
  • Precautions: Precautions for BBE and GBS include getting the flu vaccine, practicing hygiene, and seeking immediate medical help for neurological symptoms like weakness or numbness.

Read more: Guillain-Barre Syndrome 

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