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Bacteria to Solve Math Problems

  • 25 Nov 2024
  • 2 min read

Source: TH

The recent advancements in synthetic biology, particularly the engineering of bacteria to perform mathematical computations at the Saha Institute of Nuclear Physics in Kolkata, represent a significant breakthrough in the field.  

  • Researchers have engineered Escherichia coli bacteria to act as biological computers capable of solving mathematical problems, such as determining whether a number is prime or whether a letter is a vowel. 
    • This was achieved by introducing genetic circuits that can be activated by chemical inducers, allowing these bacteria to behave like artificial neural networks (ANNs). 
    • The team developed bactoneurons, engineered bacteria that function like neurons in a neural network.  
      • These bactoneurons process chemical inputs and produce fluorescent proteins based on specific computations. 
    • By converting mathematical problems into binary code represented by the presence or absence of chemical compounds, the bacteria could respond to queries with fluorescent signals indicating "yes" or "no." 
  • The engineered bacteria were capable of more than just simple tasks; they could also solve optimization problems, like calculating the number of pieces a pie could be divided into with a given number of straight cuts. 
    • This capability suggests that bacterial computers can handle progressively more complex computational tasks, potentially leading to applications in various fields.

Read more: Artificial Neural Network

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